Some of these claims have merit to them, while some of them are just hype
This conclusion is also supported by the catalytic effect of physiological concentrations of His (50 - 100 M) on the demetallation of CuHSA by EDTA observed in the current study

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The identification and structural characterization of C7orf24 as -glutamylcyclotransferase, an essential enzyme in the -glutamyl cycle
Chen, G., Fernandez, J., Mische, S
Rhythms 15 , 380392 (2000)