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The NHP model can be used to study human STI by controlling various parameters such as the infectious dose, or the time of infection that are more difficult to assess in cohort studies (Figure 4)

Under the action of certain pathological factors, the imbalance of PCD could lead to the abnormal release of a large number of inflammatory factors and mediators by a variety of immune cells, which subsequently leads to chronic synovial inflammation and the destruction of bones and joints during RA progression

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The WT and L116 HM i 3 Neuron at indicated days in differentiation were fractionated into NP40 soluble- and insoluble fractions