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The lux reaction requires reducing co-factors (NAD(P)H and FMNH 2 ), oxygen, and ATP, thus tightly coupling it to cellular metabolism 32

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49 Therefore, appropriate surface coatings are essential for the biocompatibility of AgNPs

Proc Natl Acad Sci U S A 95:30716, PMID: 9501217 Won HY, Sohn JH, Min HJ, Lee K, Woo HA, Ho YS, Park JW, Rhee SG, Hwang ES (2010) Glutathione peroxidase 1 deficiency attenuates allergen-induced airway inflammation by suppressing Th2 and Th17 cell development

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Unlike liposomal types, it offers superior stability and proven efficacy