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The most significant DNAm changes were found in genes involved in endosomal trafficking and lipid metabolism ( UBAP1, APOC2, CLPTM1, RUFY1 ), cilia function ( BBS4, DNAAF5 ), protein synthesis ( EIF1 AX ), oxidative stress ( GSTCD ), and neuroinflammation ( HMGB3, HLA-DPB1 )

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Cancer cells also take advantage of immune cells, such as macrophages and T lymphocytes, present in the tumor milieu, to obtain iron [90]

PMID: 40466876 Genes (Basel) Effect of Exogenous Hormone on R-Spondin 2 (Rspo2) and R-Spondin 3 (Rspo3) Gene Expression and Embryo Development in Chinese Soft-Shelled Turtle (Pelodiscus sinensis)