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Alpha-lipoic acid is also thought to help build up the bodys antioxidant defenses by recycling other antioxidants, including glutathione and vitamin C and vitamin E.* Taurine is involved in a variety of detoxification processes, including bile acid conjugation, a healthy response to oxidative stress, and select Phase II detoxification pathways

Cell Rep 12(1):2334

pneumoniae directly secrete a pore-forming toxin, thereby altering BBB integrity

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More specifically, NRF2 and KEAP1 have been analyzed in postmortem motor cortex and spinal cord specimens from ALS patients and a reduction in both NFE2L2 mRNA and NRF2 protein has been found in ALS patient tissues when compared to control ones