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A summary of the important clinical findings and investigations of all patients are tabulated in Table 1

Using the arginine deiminase analog ADI-PEG-20 in hepatocellular carcinoma and glioblastoma has demonstrated antitumor activity in vitro and in xenograft models and demonstrated safety and efficacy in a phase I clinical trial

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In some respects, the formation of new vessel can be viewed as an attempt by the retina to revascularize areas of capillary non-perfusion

PINK1 deficiency sustains cell proliferation by reprogramming glucose metabolism through HIF1