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PMID: 33711021 Keywords Alpha Sympathomimetics Brimonidine Trade Names: Alphagan-P, Qoliana, Lumify & generic FDA approved in 1996 Drug Class: Alpha-2 Selective Adrenergic Agonist, Antiglaucoma, Vascular decongestant Mechanism of Action: 2 adrenoreceptor agonist approximately 10-times more selective for alpha-2 receptors compared to clonidine (Cambridge, 1981) does not exhibit significant tachyphylaxis with repeated use (Lee & Kim, 2022) Indications: Prescription & OTC to treat symptoms of: open-angle glaucoma : to lower intraocular pressure or ocular hypertension (Alphagan-P, Qoliana )

Poor sleep increases cortisol and ghrelin (hunger hormone) production, which can blunt medication effects

Extracted RNA was further treated with DNase (Thermo Scientific, USA) to remove any trace of genomic DNA

(2017) 102:F256F61

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This protection aids in maintaining skin integrity and appearance, contributing to a more vibrant and youthful complexion