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Supplementary material The Supplementary Material for this article can be found online at: References 1 DongEDuHGardnerL

Cardiovascular Health Markers Secondary research findings have shown improvements in blood pressure and lipid profiles in subjects, suggesting that the benefits of this peptide may extend well beyond simple weight management

In REDEFINE 2, 73.5% of CagriSema participants reached HbA1c 6.5% versus 15.9% on placebo (treatment-policy estimand)

It acts as a substrate for sirtuins, a family of NAD+-dependent deacylases, which are key regulators of mitochondrial homeostasis

Immediate discontinuation of both agents is the standard response

Patients on 15 mg lost approximately 6 percentage points more body weight on average than those on 5 mg