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Targeting intrinsic dependency on ser/gly synthesis in combination with RT reduces tumor growth in vivo and affects the serum levels of glycine, threonine, and homocysteine In our cohort of patients with NSCLC we observed negative associations between baseline serine, glycine and threonine plasma levels and circulating lymphocytes (Fig

Moreover, there are also evidences for immune senescence, which associates the aging of immune system with failure of immune surveillance and contribution to cancer progress in older people 37

There is no doubt that precision medicine is required to treat COPD, considering its versatile and complicated profile

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IOP Conference Series: Earth and Environmental Science