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F.VagiasC.DiederichM.et al (2016)

erinaceus extracts also suppress iNOS expression, leading to reduced nitric oxide (NO) production, which is associated with chronic inflammation [118]

For example, exercise protects intestinal permeability, reducing the absorption of molecules like lipopolysaccharide (LPS) that contribute to systemic inflammationanother factor associated with CV disease, obesity, and yype 2 diabetes

The identification of reliable validated biomarkers could facilitate earlier and more accurate diagnosis and drive the development of targeted pharmacological therapies that might address the underlying pathophysiology of these diseases

10.1016/j.canlet.2016.07.035 139 RohJ.-L.KimE

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