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FIGURE 4 Action potential morphology is changed by acute application of TMAO As increasing concentrations of TMAO had a deleterious effect on the contractile recovery in the metabolic inhibition and reperfusion protocol, it was hypothesised that higher concentrations of TMAO would alter the action potential

This calcium overload activates Tau kinases, such as GSK-3 and CDK5, thereby promoting Tau phosphorylation and exacerbating the pathological process of Alzheimers disease [117]

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HYGIENE A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES A61K9/00Medicinal preparations characterised by special physical form A61K9/0012Galenical forms characterised by the site of application A61K9/0053Mouth and digestive tract, i.e