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Notably, while only ~510% of the general population carries these antibodies, an estimated 5070% of children with autism may have folate receptor antibodies [3]

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These receptors contribute to the downregulation of cytokines connected with the IL-23/IL-17 signaling cascade and hinder key molecular pathways like MAPKs and NF-B (48)

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At this stage, most N-MTS precursor proteins will either be sorted into the mitochondrial matrix, or laterally released into the IMM if they contain a hydrophobic stop-transfer signal (Mokranjac & Neupert, 2010