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The fate of the drug/carrier into the living skin, either in healthy or pathological condition, is very important information

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Preterm males are reported to have greater proinflammatory responses, oxidative stress and increased infection rates and specific immune cell phenotypical differences (22)

One of the reasons for this was the poor activity of microbial GSTs with CDNB - 1-chloro-2,4-dinitrobenzene as a model substrate for GST activity, which led to the conclusion that these enzymes are rare in unicellular organisms [81], [77]

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