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By regulating the homeostasis between the forkhead box O (FOXO) signaling pathway and the TCF signaling pathway, -catenin can also guard against oxidative stress (mainly stress response)

Studies observe how biological systems stabilize and respond under controlled conditions

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Additional S6K1 targets that are involved in translation are the negative regulator of the RNA helicase eIF4A (eukaryotic translation initiation factor 4A), PDCD4 (programmed cell death protein 4) (Dorrello et al., 2006), as well as the exon junction complex subunit SKAR (also known as POLDIP3