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However, this indiscriminate interaction with anionic cell membranes resulted in an unpredictable distribution of the cationized nanoparticles throughout the body after systemic administration, ultimately shortening the nanoparticles half-lives and leading to severe toxic effects 10,16

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Sci Rep 12(1):4673 Khan H et al (2022) -Lipoic acid, an organosulfur biomolecule a novel therapeutic agent for neurodegenerative disorders: an mechanistic perspective

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Well-known modulators of adult neurogenesis include signal transducing pathways, the neurovascular system, the immune system, metabolic factors, and epigenetic adaptations (Vallon and Chang 2014)

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Importantly, the nervous system operates mainly under aerobic conditions but cannot fully oxidize glucose and instead generates a local surplus of lactate, a phenomenon termed aerobic glycolysis ( +

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[Effect of quercetin on sodium diclofenac-induced ulceration]

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