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(2010) 5:e11957

R.MaathuisF

138,139 The main transporter genes are SLC22A12 (URAT1), SLC2A9 (GLUT9), and ABCG2 (BCRP)

Buthionine sulfoximine (BSO), a homocysteine derivative, is an irreversible GCL inhibitor that can achieve full inhibition at 10 M in enzymatic assays and lower cytosolic and nuclear GSH levels [65,69]