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Preclinical adipocyte research has investigated HGH Fragment 176-191 for its capacity to upregulate beta-3 adrenergic receptor-mediated lipolysis and inhibit fatty acid uptake via lipogenesis pathway suppression independent of systemic GH effects

Frontiers in aging neuroscience

Considering that FXR signaling is activated by CA but not by UDCA, the anti-diabetic action of BAs in Insr P1195L/ +/HFD mice might be mediated also by a FXR-independent mechanism