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Pep4 is a selected fragment of SLPI (Secretory Leucocyte Protease Inhibitor), whereas Pep4M is a modified form in which the highly reactive cysteine residues were replaced with less reactive methionine residues

The role of small intestinal bacterial overgrowth in Parkinson's disease

Physiologist 20 , 1018 (1977)

These findings align with clinical evidence showing that SIRT1 activators can alleviate fatty liver in MASLD patients, highlighting its pivotal role in lipid-related disease through the AMPK pathway 39,40