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APC or the predominant cell type in the tissue antigen is proteolytically cleaved in the cell cytoplasm (in a proteasome dependent or independent process)

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[Google Scholar] The role of oxidative stress in diabetic neuropathy: generation of free radical species in the glycation reaction and gene polymorphisms encoding antioxidant enzymes to genetic susceptibility to diabetic neuropathy in population of type I diabetic patients

After washed by PBS for three times, 4T1 cells were fixed by osmium tetroxide for 2 h, dehydrated with graded ethanol and transferred to absolute acetone for 20 min, then embedded in Spurr resin mixture to form ultrathin sections