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doi: 10.1523/JNEUROSCI.4722-05.2006

The authors acknowledged that the study was short and also did not include a placebo arm, because providing the placebo form of sublingual vitamin B12 was very difficult

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That is why clinicians often prefer conservative introductions and structured protocols rather than chaotic add-ons. A well-designed stack can reduce risk by avoiding excessive dosing of any one peptide and by supporting multiple healing bottlenecks at once