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Acyl-CoA synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 (LPCAT3) catalyze the PUFAs esterification for the subsequent incorporation into membrane phospholipids, shape the cellular lipid composition and define the ferroptotic sensitivity [9, 10]

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T1 represents less mature neutrophils, T2 denotes mature neutrophils, and T3 is comprised of a mixed subtype with varying degrees of maturity