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Women lose between 1 and 2% of their muscle mass per year from around the age of 35, and that rate accelerates through the menopause transition

Genes Dev (2007) 21(21):274761

Additionally, gut microbiome dysbiosis influences adipose inflammation through altered production of short-chain fatty acids, establishing a complex gut-adipose axis in metabolic regulation

Supports faster recovery from illness or injury

However, even if the absolute variation in cell size (standard deviation or RDW-SD) hasnt changed, once the average size (MCV) becomes much smaller (i.e., microcytosis), the same absolute variation might become more biologically meaningful or, put another way, relatively larger compared to the new, smaller mean

F.OliveiraJ