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Another study demonstrated in mouse embryonic fibroblasts that TanIIA inhibits myofibroblast activation through restoring redox homeostasis by activating Nrf2 and suppressing Nox4

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In fact, both pharmacological alteration of the mitochondrial potential (Hacker and Medler, 2008) and blocking of NCX, induced Ca 2+ signals in taste bud cells (Laskowski and Medler, 2009)