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Notably, all these minor adhesins appear to be meningococcal-specific and are not found in gonococci (Comanducci et al., 2002, Comanducci et al., 2004

Further research has found that GA inhibited the interaction between P-selectin and platelets in HL60 cells, thereby preventing platelet activation ( 2+ level by inhibiting phosphorylation of Protein Kinase C alpha (PKC) and p38 mitogen-activated protein kinase (p38 MAPK) in platelets, as well as phosphorylation of Akt and glycogen synthase kinase 3 beta (GSK3), leading to a significant reduction in ADP- and U46619-induced platelet aggregation and platelet P-selectin expression in a concentration-dependent manner (Chang et al., 2012b)

Other approaches are more appropriate

IMR90 ER:RAS cells were generated by retroviral infection of IMR90 cells and have been described elsewhere 33

No findings imply clinical relevance, therapeutic application, physiological effects, or suitability for human or veterinary use

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