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These enzymes bind toxins to glutathione molecules, making them water-soluble for easy elimination through bile or urine

doi: 10.1172/jci.insight.169515 119 ChandraAWormserGPKlempnerMSTrevinoRPCrowMKLatovNet al

Future perspectives Collectively, the preceding sections highlight zinc as a tightly regulated, compartmentalized regulator of cellular homeostasis whose disruption contributes directly to human disease

10.1016/j.taap.2012.04.006 241

Glucose starvation directly activates mTORC2 via AMPK phosphorylation of mTOR and RICTOR, 149 leading to increased AKT phosphorylation

A Fourier transform-13C-NMR spectroscopic study of pH-dependence and of charge densities