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Some products use higher B12 concentrations to account for differences in how the body processes this form. In addition, evidence published in Cureus suggests that methylcobalamin may be retained more efficiently in the body than cyanocobalamin, making it a relevant consideration for those with impaired conversion due to genetic MTHFR variations

Prakash et al., 2007

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More water gives a larger, easier-to-measure draw volume but a more dilute solution

Again, this is an area where responsible boundaries matter