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95% CI 0.08-2.84, total of 17,324 patients, figure 4)

doi: 10.1161/CIRCULATIONAHA.122.061025 135 Wu ZhangXLeng YapY

Clinical evidence demonstrates that GLP-1 receptor agonists (GLP-1RAs) confer dual benefits in DM-COPD comorbidity: reducing asthma exacerbation risk (Foer et al., 2023), while ameliorating bronchial hyperresponsiveness via PKA activation in airway epithelial cells (Rogliani et al., 2016)

the redness, soreness and heat in medical terms these responses are known as rubor, dolor and color respectively and are typical of inflammation particularly of the TH2 response