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[89] found a significant increase in midazolam exposure (respectively, up to 3.9-fold and 19-fold for C max and AUC) coupled with a relevant decrease in CL (up to 20.1-fold) among 72 healthy volunteers treated with cobicistat, owing to strong inhibitory activity on CYP3A4

10.3390/nano12020268 [DOI] [PMC free article] [PubMed] [Google Scholar] Hadinejad F., Morad H., Jahanshahi M., Zarrabi A., Pazoki-Toroudi H., Mostafavi E

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