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In rats, R -lipoic acid was more effective than S -lipoic acid in enhancing insulin-stimulated glucose transport and metabolism in skeletal muscle (110), and R -lipoic acid was more effective than R,S -lipoic acid and S -lipoic acid in preventing cataracts (111)

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Protein post-translational modifications regulated by butyrate Acetylation Lysine acetylation (Kac), a critical post-translational modification, involves the covalent attachment of acetyl groups to lysine residues, dynamically controlling protein functions, cellular signaling, and epigenetic states