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Significance of NMDA receptor-targeting compounds in neuropsychological disorders: an in-depth review

This oxidized form is reversed by thioredoxin (Trx)/Trx reductase/NADPH system, although, in RBCs, it is a very slow regeneration due to the low concentrations of Trx reductase [73]

ACSL4 regulates the metabolism of arachidonic acid and eicosapentaenoic acid, contributing to the induction of ferroptosis and driving lipid peroxidation in the pathogenesis of various diseases [29, 30]