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The liver-spleen axis The liver and the spleen are anatomically connected as that all the splenic blood flows into the liver through the portal vein [,] [Figure 10]

Biochem Pharmacol 1993

& Denison, M

This proportion varies with geography, genetic factors, gender and age

ariABalogTSoboanecSKuiBverkoVRusakGet al

Although the study was conducted in a small number of patients with NERD, dupilumab could improve nasal and asthma-related symptom scores and lung functions (Laidlaw et al., 2019), although studies with a larger sample size are needed to confirm its effectiveness