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It only affects new melanogenesis and not pre-existing pigmentation

The primary factors implicated in SIRS and CARS encompass various cytokines such as TNF, IL-1, IL-6, IL-12, MIF, sCD74, HMGB-1, as well as anti-inflammatory cytokines including IL-4, IL-10, IL-35, IL-37, TGF-, and IL-13

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Certaines molcules chappent toutefois ces attaques : elles passent au travers de la barrire intestinale avant mme dtre oxydes par les enzymes, gagnant ainsi la circulation sanguine en plein tat de fonctionnement

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