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10.1016/S0920-9964(00)00032-3 155 Valiente-PallejA.TorrellH.MuntanG.CortsM

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Other authors highlight 15 acylcarnitines, 14 amino acids, 10 biogenic amines, 1 cholestan steroid, 1 diacylglycerol, 75 phospholipids, 20 sphingomyelins and 12 triacylglycerids as differently expressed in the plasma of GBM patients compared to controls [68]

Since SOD converts superoxide to HO, its upregulation can elevate HO levels, which not only acts as a vasodilatorpotentially explaining the increased basal coronary flow observed in diabetic and diabetic-CKD animalsbut also leads to greater oxidative stress when GPX-mediated detoxification is compromised, resulting in increased tissue damage [44]