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This causes its aggregation into tangles, and this microtubule transport system disruption impairs neuronal function

Patients in the treated group (n = 30) were given ALA in oral tablets of 200 mg, three times a day (600 mg/day) while patients in the control group (n = 30) were given cellulose starch, in similar tablets, 100 mg/day, three times a day

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Targeting this pathway can limit the adaptive response from turning into a maladaptive mechanism of CKD progression

Stavri GT, Zachary IC, Baskerville PA, Martin JF, Erusalimsky JD