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Safety and immunogenicity of ChAdOx1 MERS vaccine candidate in healthy Middle Eastern adults (MERS002): an open-label, non-randomised, dose-escalation, phase 1b trial

Updated boosters made by both Pfizer and rival Moderna rolled out earlier this month for everyone 12 and older

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Furthermore, an acidic pH may induce degradation of the aspartate amino acid in the complementarity-determining regions (CDR): this may reduce or influence the ability of the mAb to bind to its epitope (123)