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Validation of mutant lines All mutants were either homozygous for the mutation when obtained or propagated to homozygosity

Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis

Biomarker Assessment and Baseline Health Profiling Before initiating or adjusting GHK-Cu dosing, baseline assessment of collagen metabolism markers, inflammatory cytokine levels, and connective tissue biomarkers provides context for expected response rates and optimal starting doses

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Enteroendocrine cells-sensory sentinels of the intestinal environment and orchestrators of mucosal immunity