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The surgeon should be prepared to do a lobectomy if the lesion is benign, or a more extensive operation and appropriate lymph node removal if, from the operative findings and examination of frozen sections, it is malignant

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492 However, during sepsis, neutrophils with an extended lifespan and impaired migration are confined to the vasculature, generating overwhelming vascular inflammation through the release of pro-inflammatory cytokines, ROS, and NETs, 493 which eventually results in endothelial dysfunction (Fig

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