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doi:10.4236/wjnse.2013.33006 30

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In 2023 the FDA placed CJC-1295 in "Category 2" of its interim 503A bulks list, meaning it identified significant safety concerns and did not permit its use in traditional pharmacy compounding

Following intravenous administration, GL is metabolized by -D-glucuronidase in hepatic lysosomes to form 3-monoglucuronyl glycyrrhetinic acid (3MGA), which subsequently undergoes enterohepatic circulation (Chen et al., 2020)

Both the cytosolic Grx1-roGFP2 and the plastidic TKTP-Grx1-roGFP2 lines exhibited a noticeable decrease in fluorescence intensity when excited at 488 nm following 24 h and 48 h AITC treatments