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These results suggest that a tapering regimen of GC therapy could be an alternative without the loss of efficacy in patients with SAH

Front Physiol 11:592950 Shivakumar M, Subbanna S, Joshi V, Basavarajappa BS (2020) Postnatal ethanol exposure activates HDAC-mediated histone deacetylation, impairs synaptic plasticity gene expression and behavior in mice

These structural features are consistent with the inward-open conformation of related transporters hGAT1, hGAT3, and hGlyT1, but distinct from the outward-tilted TM5 helix observed in the inward-open LeuT (Supplementary Fig