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Furthermore, apoptosis can be attenuated by inhibiting ferroptosis since it lowers the production of pro-apoptotic proteins ( The necrosome, a complex made up of receptor-interacting protein kinase (RIPK) 1 and RIPK3, is responsible for regulating necrosis, or necroptosis ( Inflammasome activation causes pro-inflammatory cytokines, including IL-1 and IL-18 to be released during pyroptosis, a type of programmed cell death

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The organisms are most susceptible to a particular combination of these modes of exposure depends on the species, life stage, habitat, initial oil discharge source, composition and subsequent weathering state, and environmental conditions