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Ouyang, Y

10.3390/cancers16020244 119

The PDT outcome demonstrates MBNPs superior cancer specificity, remarkable PDT efficacy, and negligible toxicity

Of this free energy, 33.2% [(61/183.6) 100] is stored in the two molecules of ATP formed

Moreover, Nrf2a key regulator of iron homeostasisis robustly activated by BL (Yao et al., 2020a,b), leading to increased production of NAD(P)H-dependent enzymes such as NQO1, suppression of NF-B signaling, and reduction of both -Syn aggregation and oxidative stressmediated neuroinflammatory damage (Lastres-Becker et al., 2016

Here, we review how mitochondrial stress pathways have pleiotropic effects on cellular and systemic homeostasis, which can comprise protective or detrimental responses during aging