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Symptoms of a B12 deficiency include weakness, fatigue, numbness or tingling in the hands and feet, difficulty walking, memory loss, and depression

It is is one of the body's most effective antioxidants as it is the only one that is intracellular

Watson DC, Bayik D, Storevik S, Moreino SS, Sprowls SA, Han J, Augustsson MT, Lauko A, Sravya P, Rsland GV, et al

L-Methionine-DL-sulfoximine has been employed to inhibit the Gln-dependent ammonia-stimulated neuronal toxicity in vitro, potentiating Gln deficit-dependent depression

doi: 10.3109/15563659809028022

1 Introduction Acute leukemias (ALs) are a group of malignant diseases of the hematopoietic system characterized by disordered proliferation and clonal expansion of immature precursors, resulting in bone marrow failure with blockage in cell differentiation processes (Swerdlow et al., 2017)