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Both saline- and GHRP-6-treated groups exhibited significant body weight loss compared to healthy sentinel rats, indicating that GHRP-6 did not prevent the cachectic weight loss induced by Dox

Patients taking certain medications (e.g., chloramphenicol may reduce the effectiveness of B12 therapy) or with risk factors for B12 deficiency (metformin use, proton pump inhibitors, nitrous oxide exposure, vegan diet) should discuss these with their healthcare provider

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During the blinded data review an indication of period effect was noted and properly registered as follow up action according to the Statistical Analysis Plan of the trial protocol