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Selenium biochemistry and its role for human health

Immunol Cell Biol 98(5):349350

This is due to the fact that obesity enhances the production of ROS in mitochondrial, which can damage the lipid membranes, proteins, and enzymes of the respiratory chain in the mitochondria, as well as DNA (77)

When the body suffers from oxidative stress, Nrf2 is activated and translocated inside the nucleus, leading to the expression of downstream antioxidant enzymes [Citation32]