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Description

Nucleoside-5-monophosphates as prodrugs of adenosine A2A receptor agonists activated by ecto-5-nucleotidase

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This is confirmed by an increased metabolic oxidative stress and cytotoxicity in response to the inhibition of glycolysis and/or the pentose phosphate pathways in combination with an inhibition of the Trx metabolism [48]

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W.GoerdtS.et al (2014)

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The novelty lies in the fact that no prior pharmacological therapy has successfully achieved muscle-to-bone reattachment

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