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Patches may be worn for up to 12 hours before discarding

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Additionally, oxidative stress can result in protein oxidation, DNA damage, nitric oxide production, and peroxidation of cell components 27

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doi: 10.1126/scitranslmed.3004970 170 BhelaSKempsellCManoharMDominguez-VillarMGriffinRBhattPet al