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Methylcobalamin B12 is also indicated in those with pernicious anemia, diabetes, neuropathy, heart disease, circadian rhythm sleep disorders, memory loss, depression, fatigue, AIDS, inflammatory bowel disease (IBD), Lyme disease, osteoporosis, tendonitis, psychiatric disorders, Alzheimers disease, liver and kidney disease, and asthma

How Often Do You Need Vitamin B12 Injections

This overlap makes B12 deficiency easy to miss during GLP-1 therapy, because both the patient and the prescriber attribute these symptoms to the medication itself rather than investigating a correctable nutritional deficit

Anyone experiencing symptoms of deficiency should consult their GP for blood tests and appropriate treatment

However, the guide will have emergency communication at all times

In the SURMOUNT-1 trial, people treated with tirzepatide lost up to 22.5% of their body weight over 72 weeks , making it even more effective than semaglutide (NEJM tirzepatide study)