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Cellular-level changes IGF-1 levels, inflammatory markers, telomere metrics are tracked through labs at the end of each 12-week cycle

Precautions commonly involve blood count monitoring, renal assessment, folic acid or vitamin B12 supplementation when specified by prescribing information, and avoidance in contraindicated patients

In contrast, the lectin-stimulated lymphocyte blast production, serum immunoglobulin levels, and cytotoxicity caused by antibody-dependent cells were unaffected