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PARP-1 inhibitor, DPQ, attenuates LPS-induced acute lung injury through inhibiting NF-B-mediated inflammatory response

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Pellatt, AJ, Bent, AH, Hornstein, N, Parseghian, C, Huey, RW, Raghav, KS, Morris, VK, Overman, MJ, Morelli, P, Willis, JA, Le, PH, Shen, JY, Kee, BK, Eluri, M, Higbie, V, Alfaro-Munoz, KD, Aziz, KE, Kell, R, Sun, R, Kopetz, S , Dasari, NV

Concurrently, the activation of CHOP/GADD153 and the T-cell death-associated protein (TDAG-51) pathways, which are two quintessential UPR routes, lead to the impairment of endothelial integrity through endothelial cell apoptosis and anoikis [48]

Data availability The data used and/or analyzed during the current study are available from the corresponding author upon reasonable request

Treatment of rapamycin strongly induces autophagy in yeast even in the presence of nutrients (62)