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Lung colony formation

Third, translational gaps between preclinical models and clinical practice are prominent: most therapeutic candidates (e.g., natural products and repurposed drugs) have only been validated in rodent models, with limited data on human renal tissue responses, optimal dosing windows, or potential drugdrug interactions in clinical settings (e.g., in patients undergoing kidney transplantation or cardiovascular surgery)

A LPS stimulation time course (0 to 6 h) was performed

For example, consumption of fava beans causes oxidative stress to erythrocytes possibly by two main toxins, vicine or convicine, thus triggering acute hemolytic episode (favism) in affected subjects 7